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首页> Aging> CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses.

CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses.

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作者： Di,Wang ^[1] ; Juan,Du ^[2] ; Yangzi,Song ^[1] ; Beibei,Wang ^[2] ; Rui,Song ^[3] ; Yu,Hao ^[2] ; Yongqin,Zeng ^[3] ; Jiang,Xiao ^[3] ; Hong,Zheng ^[4] ; Hui,Zeng ^[2] ; Hongxin,Zhao ^[3] ; Yaxian,Kong ^[2]

作者单位： Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China.;Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China. ^[1] Beijing Key Laboratory of Emerging Infectious Diseases, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China. ^[2] Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China. ^[3] Penn State Cancer Institute, Penn State University College of Medicine, Hershey, PA 17033, USA. ^[4]

关键词 CD70 T cell aging co-inhibitory molecules immunosenescence overwhelming inflammatory responses

主题词青少年(Adolescent);成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);细胞凋亡(Apoptosis);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);细胞, 培养的(Cells, Cultured);女(雌)性(Female);流式细胞术(Flow Cytometry);人类(Humans);淋巴细胞活化(Lymphocyte Activation);男(雄)性(Male);中年人(Middle Aged);增量调节(Up-Regulation);青年人(Young Adult)

DOI 10.18632/aging.103368

PMID 32559178

发布时间 2024-07-30

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Aging

Aging

2020年12卷12期

12032-12050页

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