换一批MESP2 variants contribute to conotruncal heart defects by inhibiting cardiac neural crest cell proliferation.
第一作者：
Erge,Zhang
第一单位：
Department of Pediatric Cardiovascular, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, 1665 Kongjiang Road, Shanghai, 200092, China.
作者：
医学主题词
动物(Animals);碱性螺旋-环-螺旋转录因子类(Basic Helix-Loop-Helix Transcription Factors);细胞周期(Cell Cycle);细胞系(Cell Line);细胞增殖(Cell Proliferation);减量调节(Down-Regulation);胚胎, 哺乳动物(Embryo, Mammalian);基因表达调控(Gene Expression Regulation);遗传变异(Genetic Variation);HEK293细胞(HEK293 Cells);心脏(Heart);心脏缺损, 先天性(Heart Defects, Congenital);人类(Humans);小鼠(Mice);心肌(Myocardium);神经嵴(Neural Crest);器官发生(Organogenesis);信号传导(Signal Transduction);转录因子(Transcription Factors);转录, 遗传(Transcription, Genetic);增量调节(Up-Regulation)
DOI
10.1007/s00109-020-01929-4
PMID
32572506
发布时间
2021-10-30
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