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Bmi deficiency causes oxidative stress and intervertebral disc degeneration which can be alleviated by antioxidant treatment.

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第一作者： Qunhu,Zhang

第一单位： Department of Orthopedics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.;Department of Orthopaedics, Suqian First Hospital, Suqian, Jiangsu, China.

作者： Qunhu,Zhang ^[1] ; Jie,Li ^[2] ; You,Li ^[3] ; Hui,Che ^[3] ; Ying,Chen ^[3] ; Jianghui,Dong ^[4] ; Cory J,Xian ^[5] ; Dengshun,Miao ^[6] ; Liping,Wang ^[4] ; Yongxin,Ren ^[3]

作者单位： Department of Orthopedics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.;Department of Orthopaedics, Suqian First Hospital, Suqian, Jiangsu, China. ^[1] Department of Orthopaedics, Xuzhou Central Hospital, Xuzhou Clinical College of Nanjing Medical University, The Affiliated Xuzhou Hospital of Southeast University, Xuzhou, Jiangsu, China. ^[2] Department of Orthopedics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. ^[3] Department of Hand Surgery, Department of Plastic Reconstructive Surgery, Ningbo No. 6 Hospital, Ningbo, Zhejiang, China.;UniSA Clinical and Health Sciences and UniSA Cancer Research Institute, University of South Australia, Adelaide, SA, Australia. ^[4] UniSA Clinical and Health Sciences and UniSA Cancer Research Institute, University of South Australia, Adelaide, SA, Australia. ^[5] State Key Laboratory of Reproductive Medicine, The Research Center for Bone and Stem Cells, Department of Anatomy, Histology and Embryology, Nanjing Medical University, Nanjing, Jiangsu, China. ^[6]

关键词 Bmi-1 N-acetylcysteine cell apoptosis intervertebral disc degeneration oxidative stress