Ubiquitination of interleukin-1α is associated with increased pro-inflammatory polarization of murine macrophages deficient in the E3 ligase ITCH.
第一作者:
Xi,Lin
第一单位:
Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York, USA.
作者:
主题词
动物(Animals);细胞, 培养的(Cells, Cultured);女(雌)性(Female);基因缺失(Gene Deletion);炎症(Inflammation);白细胞介素1α(Interleukin-1alpha);巨噬细胞(Macrophages);男(雄)性(Male);小鼠, 近交C57BL(Mice, Inbred C57BL);泛素(Ubiquitin);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination)
DOI
10.1074/jbc.RA120.014298
PMID
32587089
发布时间
2021-08-15
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The Journal of biological chemistry
11764-11775页
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