Congenital mesoblastic nephroma is characterised by kinase mutations including EGFR internal tandem duplications, the ETV6-NTRK3 fusion, and the rare KLHL7-BRAF fusion.

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第一作者： Manli,Zhao

第一单位： Department of Pathology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province, China.

作者： Manli,Zhao ^[1] ; Minzhi,Yin ^[2] ; Chik Hong,Kuick ^[3] ; Huiyi,Chen ^[3] ; Sze Jet,Aw ^[3] ; Khurshid,Merchant ^[3] ; Eileen Hui Qi,Ng ^[3] ; Sandini,Gunaratne ^[4] ; Amos Hong Pheng,Loh ^[5] ; Weizhong,Gu ^[1] ; Hongfeng,Tang ^[1] ; Kenneth Tou En,Chang ^[6]

作者单位： Department of Pathology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province, China. ^[1] Department of Pathology, Shanghai Children's Medical Centre, Shanghai, China. ^[2] Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore. ^[3] Lady Ridgeway Hospital for Children, Colombo, Sri Lanka. ^[4] Department of Paediatric Surgery, KK Women's and Children's Hospital.;Duke-NUS Medical School, Singapore. ^[5] Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore.;Duke-NUS Medical School, Singapore. ^[6]

关键词 EGFR immunohistochemistry EGFR internal tandem duplication KLHL7-BRAF gene fusion congenital mesoblastic nephroma pan-Trk immunohistochemistry