Integrin-linked kinase (ILK) regulates KRAS, IPP complex and Ras suppressor-1 (RSU1) promoting lung adenocarcinoma progression and poor survival.

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作者： Sofia,Nikou ^[1] ; Marina,Arbi ^[2] ; Foteinos-Ioannis D,Dimitrakopoulos ^[3] ; Chaido,Sirinian ^[3] ; Panagiota,Chadla ^[1] ; Ioanna,Pappa ^[1] ; Giannoula,Ntaliarda ^[4] ; Georgios T,Stathopoulos ^[4] ; Helen,Papadaki ^[5] ; Vasiliki,Zolota ^[1] ; Zoi,Lygerou ^[6] ; Haralabos P,Kalofonos ^[2] ; Vasiliki,Bravou ^[3]

作者单位： Department of Anatomy-Histology-Embryology, Medical School, University of Patras, 26500, Patras, Greece. ^[1] Department of General Biology, Medical School, University of Patras, 26504, Patras, Greece. ^[2] Clinical and Molecular Oncology Laboratory, Division of Oncology, Medical School, University of Patras, 26504, Rio, Greece. ^[3] Laboratory for Molecular Respiratory Carcinogenesis, Department of Physiology, Faculty of Medicine, University of Patras, 2504, Rio, Achaia, Greece. ^[4] Comprehensive Pneumology Center (CPC) and Institute for Lung Biology and Disease (iLBD), University Hospital, Ludwig-Maximilians University and Helmholtz Zentrum München, Member of the German Center for Lung Research (DZL), Munich, Bavaria, Germany. ^[5] Department of Pathology, University Hospital of Patras, 26504, Patras, Greece. ^[6] Division of Oncology, Department of Internal Medicine, University Hospital of Patras, 26504, Rio, Greece. ^[7] Department of Anatomy-Histology-Embryology, Medical School, University of Patras, 26500, Patras, Greece. vibra@upatras.gr. ^[8]

关键词 ILK KRAS Lung cancer PARVB PINCH Ras suppressor-1