Folic acid supplementation in children with sickle cell disease: study protocol for a double-blind randomized cross-over trial.

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作者： Brock A,Williams ^[1] ; Heather,McCartney ^[2] ; Erin,Adams ^[3] ; Angela M,Devlin ^[4] ; Joel,Singer ^[2] ; Suzanne,Vercauteren ^[3] ; John K,Wu ^[5] ; Crystal D,Karakochuk ^[6]

作者单位： Food, Nutrition, and Health, Faculty of Land and Food Systems, The University of British Columbia, 2205 East Mall, Vancouver, British Columbia, V6T 1Z4, Canada. ^[1] BC Children's Hospital Research Institute, 950 W 28th Avenue, Vancouver, British Columbia, V5Z 4H4, Canada. ^[2] Department of Pediatrics, Faculty of Medicine, The University of British Columbia, 4480 Oak Street, Vancouver, British Columbia, V6H 3V4, Canada. ^[3] Department of Pharmacy, BC Children's Hospital, 4480 Oak Street, Vancouver, British Columbia, V6H 3V4, Canada. ^[4] School of Population and Public Health, The University of British Columbia, 2206 East Mall, Vancouver, British Columbia, V6T 1Z3, Canada. ^[5] The Centre for Health Evaluation and Outcome Science, St. Paul's Hospital, 588 - 1081 Burrard Street, Vancouver, British Columbia, V6Z 1Y6, Canada. ^[6] Department of Pathology and Laboratory Medicine, BC Children's Hospital, 4480 Oak Street, Vancouver, British Columbia, V6H 3V4, Canada. ^[7] Food, Nutrition, and Health, Faculty of Land and Food Systems, The University of British Columbia, 2205 East Mall, Vancouver, British Columbia, V6T 1Z4, Canada. crystal.karakochuk@ubc.ca. ^[8] BC Children's Hospital Research Institute, 950 W 28th Avenue, Vancouver, British Columbia, V5Z 4H4, Canada. crystal.karakochuk@ubc.ca. ^[9]

关键词 Folic acid Micronutrient supplementation Nutrition Pediatrics Randomized control trial Sickle cell disease