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Targeting CD70 with cusatuzumab eliminates acute myeloid leukemia stem cells in patients treated with hypomethylating agents.

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第一作者： Carsten,Riether

第一单位： Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. carsten.riether@insel.ch.;Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland. carsten.riether@insel.ch.

作者： Carsten,Riether ^[1] ; Thomas,Pabst ^[2] ; Sabine,Höpner ^[3] ; Ulrike,Bacher ^[4] ; Magdalena,Hinterbrandner ^[5] ; Yara,Banz ^[6] ; Rouven,Müller ^[7] ; Markus G,Manz ^[7] ; Walid H,Gharib ^[8] ; David,Francisco ^[8] ; Remy,Bruggmann ^[8] ; Luc,van Rompaey ^[9] ; Mahan,Moshir ^[9] ; Tim,Delahaye ^[9] ; Domenica,Gandini ^[9] ; Ellen,Erzeel ^[9] ; Anna,Hultberg ^[9] ; Samson,Fung ^[10] ; Hans,de Haard ^[9] ; Nicolas,Leupin ^[9] ; Adrian F,Ochsenbein ^[11]

作者单位： Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. carsten.riether@insel.ch.;Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland. carsten.riether@insel.ch. ^[1] Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. ^[2] Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.;Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland. ^[3] Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. ^[4] Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.;Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland.;Graduate School of Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland. ^[5] Institute of Pathology, University of Bern, Bern, Switzerland. ^[6] Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland. ^[7] Interfaculty Bioinformatics Unit and SIB Swiss Institute of Bioinformatics, University of Bern, Bern, Switzerland. ^[8] argenx BVBA, Zwijnaarde, Belgium. ^[9] argenx BVBA, Zwijnaarde, Belgium.;Fung Consulting Healthcare & Life Sciences, Eching, Germany. ^[10] Department of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. adrian.ochsenbein@insel.ch.;Department for BioMedical Research (DBMR), University of Bern, Bern, Switzerland. adrian.ochsenbein@insel.ch. ^[11]