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Changes in heart morphometric parameters over the course of a monocrotaline-induced pulmonary arterial hypertension rat model.

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第一作者： Mateusz K,Hołda

第一单位： HEART-Heart Embryology and Anatomy Research Team, Department of Anatomy, Jagiellonian University Medical College, Kopernika 12, 31-034, Kraków, Poland. mkh@onet.eu.;Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, Kraków, Poland. mkh@onet.eu.;Division of Cardiovascular Sciences, The University of Manchester, Manchester, UK. mkh@onet.eu.

作者： Mateusz K,Hołda ^[1] ; Elżbieta,Szczepanek ^[2] ; Joanna,Bielawska ^[3] ; Natalia,Palka ^[4] ; Dorota,Wojtysiak ^[5] ; Paulina,Frączek ^[6] ; Michał,Nowakowski ^[7] ; Natalia,Sowińska ^[7] ; Zbigniew,Arent ^[7] ; Piotr,Podolec ^[4] ; Grzegorz,Kopeć ^[4]

作者单位： HEART-Heart Embryology and Anatomy Research Team, Department of Anatomy, Jagiellonian University Medical College, Kopernika 12, 31-034, Kraków, Poland. mkh@onet.eu.;Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, Kraków, Poland. mkh@onet.eu.;Division of Cardiovascular Sciences, The University of Manchester, Manchester, UK. mkh@onet.eu. ^[1] HEART-Heart Embryology and Anatomy Research Team, Department of Anatomy, Jagiellonian University Medical College, Kopernika 12, 31-034, Kraków, Poland. ^[2] Manor Veterinary Clinic, Folkestone, UK. ^[3] Department of Cardiac and Vascular Diseases, Jagiellonian University Medical College, Kraków, Poland. ^[4] Department of Animal Genetics, Breeding and Ethology, University of Agriculture in Cracow, Kraków, Poland. ^[5] Department of Clinical Oncology, University Hospital, Kraków, Poland. ^[6] Center of Experimental and Innovative Medicine, University Center of Veterinary Medicine JU-AU, University of Agriculture in Cracow, Kraków, Poland. ^[7]

关键词 Cardiac remodelling Left ventricle mass loss Monocrotaline-induced PAH Pulmonary hypertension Right ventricular failure

主题词动物(Animals);心室(Heart Ventricles);高血压, 肺性(Hypertension, Pulmonary);野百合碱(Monocrotaline);肺动脉(Pulmonary Artery);大鼠(Rats)

DOI 10.1186/s12967-020-02440-7

PMID 32605656

发布时间 2021-05-14

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