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3D Correlative Cryo-Structured Illumination Fluorescence and Soft X-ray Microscopy Elucidates Reovirus Intracellular Release Pathway.

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第一作者： Ilias,Kounatidis

第一单位： Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK.

作者： Ilias,Kounatidis ^[1] ; Megan L,Stanifer ^[2] ; Michael A,Phillips ^[3] ; Perrine,Paul-Gilloteaux ^[4] ; Xavier,Heiligenstein ^[5] ; Hongchang,Wang ^[1] ; Chidinma A,Okolo ^[1] ; Thomas M,Fish ^[1] ; Matthew C,Spink ^[1] ; David I,Stuart ^[6] ; Ilan,Davis ^[7] ; Steeve,Boulant ^[8] ; Jonathan M,Grimes ^[6] ; Ian M,Dobbie ^[7] ; Maria,Harkiolaki ^[9]

作者单位： Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK. ^[1] Department of Infectious Diseases, Molecular Virology, Heidelberg University Hospital, 69120 Heidelberg, Germany. ^[2] Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK; Micron Advanced Imaging Consortium, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK; Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK. ^[3] Université de Nantes, CNRS, INSERM, l'institut du thorax, Nantes, France; Nantes Université, CHU Nantes, Inserm, CNRS, SFR Santé, Inserm UMS 016, CNRS UMS3556, Nantes, France. ^[4] CryoCapCell, 155 Boulevard de l'hôpital, 75013 Paris, France. ^[5] Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK; Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN, UK. ^[6] Micron Advanced Imaging Consortium, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. ^[7] Department of Infectious Diseases, Virology, Heidelberg University Hospital, 69120 Heidelberg, Germany; Research Group "Cellular polarity and viral infection," German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. ^[8] Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, UK. Electronic address: maria.harkiolaki@diamond.ac.uk. ^[9]

关键词 CLXT X-ray tomography correlative imaging reovirus biology structured illumination microscopy