换一批
换一批Integrated pharmaco-proteogenomics defines two subgroups in isocitrate dehydrogenase wild-type glioblastoma with prognostic and therapeutic opportunities.
作者：
Sejin,Oh [1]
;
Jeonghun,Yeom [2]
;
Hee Jin,Cho [3]
;
Ju-Hwa,Kim [4]
;
Seon-Jin,Yoon [5]
;
Hakhyun,Kim [6]
;
Jason K,Sa [7]
;
Shinyeong,Ju [8]
;
Hwanho,Lee [2]
;
Myung Joon,Oh [9]
;
Wonyeop,Lee [2]
;
Yumi,Kwon [10]
;
Honglan,Li [3]
;
Seunghyuk,Choi [11]
;
Jang Hee,Han [2]
;
Jong Hee,Chang [12]
;
Eunsuk,Choi [1]
;
Jayeon,Kim [13]
;
Nam-Gu,Her [3]
;
Se Hoon,Kim [11]
;
Seok-Gu,Kang [13]
;
Eunok,Paek [14]
;
Do-Hyun,Nam [13]
;
Cheolju,Lee [1]
;
Hyun Seok,Kim [15]
作者单位：
Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.
[1]
Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.
[2]
Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea.
[3]
Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Korea.
[4]
Convergence Medicine Research Center, Asan Institute for Life Sciences, Seoul, Korea.
[5]
Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.
[6]
Precision Medicine Research Institute, Samsung Medical Center, Seoul, Korea.
[7]
Graduate Program for Nanomedical Science, Yonsei University, Seoul, Korea.
[8]
Department of Biochemistry and Molecular Biology, Yonsei University College of Medicine, Seoul, Korea.
[9]
Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Korea.
[10]
Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul, Korea.
[11]
Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.
[12]
Department of Computer Science, Hanyang University, Seoul, Korea.
[13]
School of Computer Science and Engineering, Soongsil University, Seoul, Korea.
[14]
Department of Medical Science, Yonsei University Graduate School, Seoul, Korea.
[15]
Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
[16]
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
[17]
Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.
[18]
Department of Computer Science, Hanyang University, Seoul, Korea. eunokpaek@hanyang.ac.kr.
[19]
Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea. nsnam@skku.edu.
[20]
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. nsnam@skku.edu.
[21]
Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea. nsnam@skku.edu.
[22]
Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea. clee270@kist.re.kr.
[23]
Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Korea. clee270@kist.re.kr.
[24]
Department of Converging Science and Technology, KHU-KIST, Kyung Hee University, Seoul, Korea. clee270@kist.re.kr.
[25]
Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea. hsfkim@yuhs.ac.
[26]
Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea. hsfkim@yuhs.ac.
[27]
主题词
苯甲酰胺类(Benzamides);脑肿瘤(Brain Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);胶质母细胞瘤(Glioblastoma);人类(Humans);异柠檬酸脱氢酶(Isocitrate Dehydrogenase);Kaplan-Meiers评估(Kaplan-Meier Estimate);吗啉类(Morpholines);突变(Mutation);预后(Prognosis);蛋白激酶抑制剂(Protein Kinase Inhibitors);蛋白质组学(Proteomics);嘧啶类(Pyrimidines)
DOI
10.1038/s41467-020-17139-y
PMID
32620753
发布时间
2021-07-03
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Nature communications
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