Translational engagement of lysophosphatidic acid receptor 1 in skin fibrosis: from dermal fibroblasts of patients with scleroderma to tight skin 1 mouse.

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第一作者： Laetitia,Ledein

第一单位： Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France.

作者： Laetitia,Ledein ^[1] ; Bertrand,Léger ^[1] ; Clara,Dees ^[2] ; Christian,Beyer ^[2] ; Alfiya,Distler ^[2] ; Serena,Vettori ^[3] ; Rachid,Boukaiba ^[4] ; Jean Pierre,Bidouard ^[1] ; Matthias,Schaefer ^[5] ; Josef,Pernerstorfer ^[5] ; Hartmut,Ruetten ^[5] ; Alexandre,Jagerschmidt ^[1] ; Philip,Janiak ^[1] ; Jörg H W,Distler ^[2] ; Oliver,Distler ^[6] ; Stéphane,Illiano ^[1]

作者单位： Cardiovascular & Metabolism Unit, Sanofi, Chilly-Mazarin, France. ^[1] Department of Internal Medicine 3, Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany. ^[2] Department of Clinical and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy. ^[3] IDD Department, Sanofi, Vitry-sur-Seine, France. ^[4] R&D Diabetes Division, Sanofi, Frankfurt, Germany. ^[5] Department of Rheumatology, University Hospital Zurich, Zürich, Switzerland. ^[6]

关键词 LPA1 receptor SAR100842 fibrosis lysophosphatidic acid systemic sclerosis tight skin mouse