Adoptive Treg cell-based immunotherapy: Frontier therapeutic aspects in rheumatoid arthritis.

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第一作者： Mahdi,Zavvar

第一单位： Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.;Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

作者： Mahdi,Zavvar ^[1] ; Sara,Assadiasl ^[2] ; Sina,Zargaran ^[3] ; Maryam,Akhtari ^[4] ; Behzad,Poopak ^[5] ; Rassoul,Dinarvand ^[6] ; Yousef,Fatahi ^[6] ; Lobat,Tayebi ^[7] ; Narjes,Soleimanifar ^[2] ; Mohammad Hossein,Nicknam ^[8]

作者单位： Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.;Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ^[1] Molecular Immunology Research Centre, Tehran University of Medical Sciences, Tehran, Iran. ^[2] Faculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. ^[3] Department of Cell & Molecular Biology, School of Biology, College of Science, University of Tehran, Tehran, Iran. ^[4] Department of Hematology, Faculty of Paramedical Sciences, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. ^[5] Department of Pharmaceutical Nanotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.;Nanotechnology Research Centre, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. ^[6] Marquette University School of Dentistry, Milwaukee, WI 53233, USA. ^[7] Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.;Molecular Immunology Research Centre, Tehran University of Medical Sciences, Tehran, Iran. ^[8]

关键词 Foxp3 Treg Treg cell immunotherapy Treg cell modulation adoptive cell therapy expansion of Treg cell immunotherapy induced antigen-specific Treg cell regulatory T cell rheumatoid arthritis

主题词关节炎, 类风湿(Arthritis, Rheumatoid);人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory)

DOI 10.2217/imt-2020-0071

PMID 32635779

发布时间 2021-11-08

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