The brains of aged mice are characterized by altered tissue diffusion properties and cerebral microbleeds.

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作者： Erik N,Taylor ^[1] ; Nasi,Huang ^[2] ; Jonathan,Wisco ^[3] ; Yandan,Wang ^[4] ; Kathleen G,Morgan ^[5] ; James A,Hamilton ^[6]

作者单位： Department of Radiology, University of New Mexico, Albuquerque, NM, USA. eriktaylor@salud.unm.edu. ^[1] Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA, USA. eriktaylor@salud.unm.edu. ^[2] Department of Biomedical Engineering, Boston University, Boston, MA, USA. eriktaylor@salud.unm.edu. ^[3] Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA, USA. ^[4] Department of Biomedical Engineering, Boston University, Boston, MA, USA. ^[5] Department of Anatomy & Neurobiology, Boston University School of Medicine, Boston, MA, USA. ^[6] Department of Health Sciences, Boston University, Boston, MA, USA. ^[7] Department of Physiology & Biophysics, Boston University School of Medicine, Boston, MA, USA. jhamilt@bu.edu. ^[8] Department of Biomedical Engineering, Boston University, Boston, MA, USA. jhamilt@bu.edu. ^[9]

关键词 Aging Brain imaging Cerebral microbleeds (CMBs)Gradient-recalled echo MRI, diffusion tensor imaging Vascular contributions to cognitive impairment and dementia (VCID)

主题词动物(Animals);脑(Brain);脑出血(Cerebral Hemorrhage);弥散磁共振成像(Diffusion Magnetic Resonance Imaging);磁共振成像(Magnetic Resonance Imaging);小鼠(Mice)

DOI 10.1186/s12967-020-02441-6

PMID 32641073

发布时间 2021-05-14

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