换一批LRP1 knockdown aggravates Aβ<sub>1-42</sub>-stimulated microglial and astrocytic neuroinflammatory responses by modulating TLR4/NF-κB/MAPKs signaling pathways.
第一作者：
Yingying,He
第一单位：
Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
作者：
医学主题词
淀粉样β肽类(Amyloid beta-Peptides);动物(Animals);星形细胞(Astrocytes);细胞系(Cell Line);细胞, 培养的(Cells, Cultured);细胞因子类(Cytokines);基因敲低技术(Gene Knockdown Techniques);炎症(Inflammation);炎症介导素类(Inflammation Mediators);MAP激酶信号系统(MAP Kinase Signaling System);小鼠(Mice);小神经胶质细胞(Microglia);NF-κB(NF-kappa B);肽碎片(Peptide Fragments);蛋白激酶抑制剂(Protein Kinase Inhibitors);Toll样受体4(Toll-Like Receptor 4)
DOI
10.1016/j.yexcr.2020.112166
PMID
32645395
发布时间
2021-01-27
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