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Stimuli-Responsive Small-on-Large Nanoradiosensitizer for Enhanced Tumor Penetration and Radiotherapy Sensitization.

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第一作者： Wenhui,Fu

第一单位： Laboratory for Micro-sized Functional Materials, Department of Chemistry and College of Elementary Education, Capital Normal University, Beijing 100048, China.;CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China.;CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China.

作者： Wenhui,Fu ^[1] ; Xiao,Zhang ^[2] ; Linqiang,Mei ^[3] ; Ruyi,Zhou ^[4] ; Wenyan,Yin ^[2] ; Qiang,Wang ^[5] ; Zhanjun,Gu ^[3] ; Yuliang,Zhao ^[3]

作者单位： Laboratory for Micro-sized Functional Materials, Department of Chemistry and College of Elementary Education, Capital Normal University, Beijing 100048, China.;CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China.;CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. ^[1] CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China.;CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. ^[2] CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China.;Center of Materials Science and Optoelectronics Engineering, College of Materials Science and Optoelectronic Technology, University of Chinese Academy of Sciences, Beijing 100049, China. ^[3] CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100049, China. ^[4] Laboratory for Micro-sized Functional Materials, Department of Chemistry and College of Elementary Education, Capital Normal University, Beijing 100048, China.;CAS Key Laboratory of Nano-Bio Interface, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215123, China. ^[5]

关键词 enhanced tumor penetration intratumoral biodegradation and disassembly nanoradiosensitization stimuli response synergistic therapies

医学主题词铪(Hafnium);人类(Humans);过氧化氢(Hydrogen Peroxide);纳米粒子(Nanoparticles);肿瘤(Neoplasms);光疗法(Phototherapy);肿瘤微环境(Tumor Microenvironment)

DOI 10.1021/acsnano.0c03094

PMID 32658453

发布时间 2021-05-14

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准确一般字义偏差语意偏离译文作用小提交