作者：
Jiandong,Huo [1]
;
Audrey,Le Bas [2]
;
Reinis R,Ruza [3]
;
Helen M E,Duyvesteyn [2]
;
Halina,Mikolajek [3]
;
Tomas,Malinauskas [2]
;
Tiong Kit,Tan [2]
;
Pramila,Rijal [4]
;
Maud,Dumoux [2]
;
Philip N,Ward [5]
;
Jingshan,Ren [5]
;
Daming,Zhou [6]
;
Peter J,Harrison [1]
;
Miriam,Weckener [2]
;
Daniel K,Clare [3]
;
Vinod K,Vogirala [2]
;
Julika,Radecke [2]
;
Lucile,Moynié [2]
;
Yuguang,Zhao [3]
;
Javier,Gilbert-Jaramillo [1]
;
Michael L,Knight [4]
;
Julia A,Tree [4]
;
Karen R,Buttigieg [4]
;
Naomi,Coombes [1]
;
Michael J,Elmore [2]
;
Miles W,Carroll [7]
;
Loic,Carrique [7]
;
Pranav N M,Shah [8]
;
William,James [8]
;
Alain R,Townsend [8]
;
David I,Stuart [8]
;
Raymond J,Owens [8]
;
James H,Naismith [2]
作者单位：
Structural Biology, The Rosalind Franklin Institute, Harwell Science & Innovation Campus, Didcot, UK.
[1]
Division of Structural Biology, University of Oxford, The Wellcome Centre for Human Genetics, Headington, Oxford, UK.
[2]
Protein Production UK, The Rosalind Franklin Institute - Diamond Light Source, The Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK.
[3]
Diamond Light Source Ltd, Harwell Science & Innovation Campus, Didcot, UK.
[4]
MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
[5]
Centre for Translational Immunology, Chinse Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK.
[6]
Sir William Dunn School of Pathology, University of Oxford, Oxford, UK.
[7]
National Infection Service, Public Health England, Porton Down, Salisbury, UK.
[8]
Structural Biology, The Rosalind Franklin Institute, Harwell Science & Innovation Campus, Didcot, UK. raymond.owens@rc-harwell.ac.uk.
[9]
Division of Structural Biology, University of Oxford, The Wellcome Centre for Human Genetics, Headington, Oxford, UK. raymond.owens@rc-harwell.ac.uk.
[10]
Protein Production UK, The Rosalind Franklin Institute - Diamond Light Source, The Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK. raymond.owens@rc-harwell.ac.uk.
[11]
Structural Biology, The Rosalind Franklin Institute, Harwell Science & Innovation Campus, Didcot, UK. naismith@strubi.ox.ac.uk.
[12]
Division of Structural Biology, University of Oxford, The Wellcome Centre for Human Genetics, Headington, Oxford, UK. naismith@strubi.ox.ac.uk.
[13]
Protein Production UK, The Rosalind Franklin Institute - Diamond Light Source, The Research Complex at Harwell, Harwell Science & Innovation Campus, Didcot, UK. naismith@strubi.ox.ac.uk.
[14]
主题词
氨基酸序列(Amino Acid Sequence);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);抗体亲和力(Antibody Affinity);抗原抗体反应(Antigen-Antibody Reactions);结合, 竞争性(Binding, Competitive);冠状病毒感染(Coronavirus Infections);冷冻电子显微镜检查(Cryoelectron Microscopy);结晶学, X线(Crystallography, X-Ray);表位(Epitopes);人类(Humans);免疫球蛋白Fc片段(Immunoglobulin Fc Fragments);模型, 分子(Models, Molecular);疾病大流行(Pandemics);肽库(Peptide Library);肽基二肽酶A(Peptidyl-Dipeptidase A);肺炎, 病毒性(Pneumonia, Viral);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);受体, 病毒(Receptors, Virus);重组融合蛋白质类(Recombinant Fusion Proteins);序列同源性, 氨基酸(Sequence Homology, Amino Acid)
DOI
10.1038/s41594-020-0469-6
PMID
32661423
发布时间
2024-03-20
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