换一批
换一批Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma.
作者：
Johannes,Gojo [1]
;
Bernhard,Englinger [2]
;
Li,Jiang [2]
;
Jens M,Hübner [3]
;
McKenzie L,Shaw [2]
;
Olivia A,Hack [2]
;
Sibylle,Madlener [4]
;
Dominik,Kirchhofer [5]
;
Ilon,Liu [2]
;
Jason,Pyrdol [6]
;
Volker,Hovestadt [7]
;
Emanuele,Mazzola [8]
;
Nathan D,Mathewson [6]
;
Maria,Trissal [2]
;
Daniela,Lötsch [9]
;
Christian,Dorfer [10]
;
Christine,Haberler [11]
;
Angela,Halfmann [12]
;
Lisa,Mayr [4]
;
Andreas,Peyrl [4]
;
Rene,Geyeregger [12]
;
Benjamin,Schwalm [3]
;
Monica,Mauermann [3]
;
Kristian W,Pajtler [13]
;
Till,Milde [14]
;
Marni E,Shore [7]
;
Jack E,Geduldig [15]
;
Kristine,Pelton [15]
;
Thomas,Czech [10]
;
Orr,Ashenberg [16]
;
Kai W,Wucherpfennig [6]
;
Orit,Rozenblatt-Rosen [17]
;
Sanda,Alexandrescu [18]
;
Keith L,Ligon [19]
;
Stefan M,Pfister [13]
;
Aviv,Regev [20]
;
Irene,Slavc [4]
;
Walter,Berger [21]
;
Mario L,Suvà [7]
;
Marcel,Kool [22]
;
Mariella G,Filbin [23]
作者单位：
Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215, USA; Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090 Vienna, Austria.
[1]
Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
[2]
Hopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
[3]
Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090 Vienna, Austria.
[4]
Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090 Vienna, Austria; Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.
[5]
Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA.
[6]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
[7]
Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[8]
Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, Medical University of Vienna, 1090 Vienna, Austria; Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria; Department of Neurosurgery, Medical University of Vienna, 1090 Vienna, Austria.
[9]
Department of Neurosurgery, Medical University of Vienna, 1090 Vienna, Austria.
[10]
Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University of Vienna, 1090 Vienna, Austria.
[11]
Clinical Cell Biology, Children's Cancer Research Institute (CCRI), 1090 Vienna, Austria.
[12]
Hopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Department of Paediatric Haematology and Oncology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
[13]
Hopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany; Department of Paediatric Haematology and Oncology, Heidelberg University Hospital, 69120 Heidelberg, Germany.
[14]
Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[15]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA.
[16]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
[17]
Department of Pathology, Boston Children's Hospital, Boston, MA 02115, USA.
[18]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Oncologic Pathology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, Boston Children's Hospital, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
[19]
Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02140, USA.
[20]
Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, 1090 Vienna, Austria.
[21]
Hopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, the Netherlands.
[22]
Department of Pediatric Oncology, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address: mariella.filbin@childrens.harvard.edu.
[23]
主题词
细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);中枢神经系统肿瘤(Central Nervous System Neoplasms);儿童(Child);室管膜瘤(Ependymoma);基因组学(Genomics);人类(Humans);神经元(Neurons);预后(Prognosis);序列分析, RNA(Sequence Analysis, RNA);单细胞分析(Single-Cell Analysis);存活率分析(Survival Analysis)
DOI
10.1016/j.ccell.2020.06.004
PMID
32663469
发布时间
2024-04-28
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Cancer cell
Cancer cell
44-59.e9页
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