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Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV.

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第一作者: Sebastian J,Theobald
第一单位: Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.;Laboratory of Regenerative Immune Therapies Applied, Excellence Cluster REBIRTH, Hannover Medical School, Hannover, Germany.;German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.
作者单位: Clinic of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.;Laboratory of Regenerative Immune Therapies Applied, Excellence Cluster REBIRTH, Hannover Medical School, Hannover, Germany.;German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany. [1] Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.;Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany. [2] Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany. [3] Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany. [4] Institute of Virology, University Erlangen-Nürnberg, Erlangen, Germany. [5] Structural Virology Unit, Department of Virology, Institut Pasteur, Paris, France; CNRS UMR 3569, Paris, France. [6] Research Facility Cell Sorting, Hannover Medical School, Hannover, Germany. [7] Laboratory of Experimental Immunology, Institute of Virology, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.;Center for Molecular Medicine Cologne (CMMC), University Hospital of Cologne, Cologne, Germany.;German Centre for Infection Research, Partner Site Bonn-Cologne, Cologne, Germany. [8] German Centre for Infection Research (DZIF), Partner Site Hannover-Braunschweig, Hannover, Germany.;Instiute of Virology, Hannover Medical School, Hannover, Germany. [9] Department of Obstetrics, Clinic of Gynecology and Reproductive Medicine, and Obstetrics, Hannover Medical School, Hannover, Germany. [10] Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany. [11] Biostatistics Group, Helmholtz Centre for Infection Research, Braunschweig, Germany.;Institute for Information Engineering, Ostfalia University, Wolfenbuettel, Germany. [12] Department of Systems Immunology and Braunschweig Integrated Centre of Systems Biology (BRICS), Helmholtz Centre for Infection Research, Braunschweig, Germany.;Institute for Biochemistry, Biotechnology and Bioinformatics, Technische Universität Braunschweig, Braunschweig, Germany.;Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany. [13]
DOI 10.1371/journal.ppat.1008560
PMID 32667948
发布时间 2021-03-01
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