Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells.

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作者： Yuichi,Iida ^[1] ; Rintaro,Yoshikawa ^[2] ; Akihiko,Murata ^[3] ; Hitoshi,Kotani ^[4] ; Yasuhiro,Kazuki ^[5] ; Mitsuo,Oshimura ^[6] ; Yumi,Matsuzaki ^[2] ; Mamoru,Harada ^[4]

作者单位： Immunology, Shimane University Faculty of Medicine Graduate School of Medicine, Izumo, Japan yiida@med.shimane-u.ac.jp. ^[1] Life Science, Shimane University Faculty of Medicine Graduate School of Medicine, Izumo, Shimane, Japan. ^[2] Molecular and Cellular Biology, Tottori University Faculty of Medicine, Yonago, Tottori, Japan. ^[3] Immunology, Shimane University Faculty of Medicine Graduate School of Medicine, Izumo, Japan. ^[4] Biomedical Science, Tottori University Faculty of Medicine, Yonago, Tottori, Japan. ^[5] Chromosome Engineering Research Center, Tottori University, Yonago, Tottori, Japan. ^[6]

关键词 cell engineering dendritic cells immunotherapy programmed cell death 1 receptor tumor microenvironment

主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);趋化因子CCL19(Chemokine CCL19);女(雌)性(Female);人类(Humans);间质干细胞移植(Mesenchymal Stem Cell Transplantation);间质干细胞(Mesenchymal Stem Cells);小鼠(Mice)

DOI 10.1136/jitc-2020-000582

PMID 32675195

发布时间 2021-09-20

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Journal for immunotherapy of cancer

2020年8卷2期

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Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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Local injection of CCL19-expressing mesenchymal stem cells augments the therapeutic efficacy of anti-PD-L1 antibody by promoting infiltration of immune cells.

Journal for immunotherapy of cancer

相似文献

Journal for immunotherapy of cancer

相关期刊

检索历史清除