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HEDGES error-correcting code for DNA storage corrects indels and allows sequence constraints.

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第一作者： William H,Press

第一单位： Department of Computer Science, The University of Texas at Austin, Austin, TX 78712; wpress@cs.utexas.edu.;Department of Integrative Biology, The University of Texas at Austin, Austin, TX 78712.

作者： William H,Press ^[1] ; John A,Hawkins ^[2] ; Stephen K,Jones ^[3] ; Jeffrey M,Schaub ^[3] ; Ilya J,Finkelstein ^[3]

作者单位： Department of Computer Science, The University of Texas at Austin, Austin, TX 78712; wpress@cs.utexas.edu.;Department of Integrative Biology, The University of Texas at Austin, Austin, TX 78712. ^[1] Oden Institute of Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78712.;Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.;Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712. ^[2] Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712.;Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712. ^[3]

关键词 DNA Reed–Solomon error-correcting code indel information storage

医学主题词 DNA(DNA);DNA复制(DNA Replication);INDEL突变(INDEL Mutation);信息存储和检索(Information Storage and Retrieval);模型, 统计学(Models, Statistical)

DOI 10.1073/pnas.2004821117

PMID 32675237

发布时间 2022-11-02

基金项目

F32 AG053051/AG/NIA NIH HHS/United States R01 GM120554/GM/NIGMS NIH HHS/United States R01 GM124141/GM/NIGMS NIH HHS/United States

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