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首页> Cell death & disease> MBNL1 reverses the proliferation defect of skeletal muscle satellite cells in myotonic dystrophy type 1 by inhibiting autophagy via the mTOR pathway.

MBNL1 reverses the proliferation defect of skeletal muscle satellite cells in myotonic dystrophy type 1 by inhibiting autophagy via the mTOR pathway.

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作者： Kai-Yi,Song ^[1] ; Xiu-Ming,Guo ^[2] ; Hui-Qi,Wang ^[1] ; Lei,Zhang ^[1] ; Si-Yuan,Huang ^[2] ; Ying-Chao,Huo ^[1] ; Gang,Zhang ^[1] ; Jin-Zhou,Feng ^[1] ; Rong-Rong,Zhang ^[3] ; Yue,Ma ^[1] ; Qing-Zhe,Hu ^[1] ; Xin-Yue,Qin ^[1]

作者单位： Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, 1 Yixueyuan Road, Yuzhong District, 400016, Chongqing, China. ^[1] Rehabilitation & Sports Medicine Research Institute of Zhejiang Province, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, 310014, Hangzhou, China. ^[2] Department of Cerebrovascular Diseases, The first people's hospital of Zunyi, The third affiliate hospital of Zunyi medical university, Number 98, Fenghuang Road, 563000, Zunyi, Guizhou Province, China. ^[3] Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, 1 Yixueyuan Road, Yuzhong District, 400016, Chongqing, China. qinxinyue2019168@sina.com. ^[4]

主题词自噬(Autophagy);细胞系(Cell Line);细胞核(Cell Nucleus);细胞增殖(Cell Proliferation);女(雌)性(Female);基因组(Genome);人类(Humans);男(雄)性(Male);中年人(Middle Aged);营养不良性肌强直(Myotonic Dystrophy);磷酰化(Phosphorylation);RNA结合蛋白质类(RNA-Binding Proteins);卫星细胞, 骨骼肌(Satellite Cells, Skeletal Muscle);信号传导(Signal Transduction);西罗莫司(Sirolimus);TOR丝氨酸-苏氨酸激酶(TOR Serine-Threonine Kinases)

DOI 10.1038/s41419-020-02756-8

PMID 32683410

发布时间 2021-12-04

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Cell death & disease

Cell death & disease

2020年11卷7期

545页

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