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Inhibitors of a Na<sup>+</sup>-pumping NADH-ubiquinone oxidoreductase play multiple roles to block enzyme function.

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第一作者： Takahiro,Masuya

第一单位： Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan.

作者： Takahiro,Masuya ^[1] ; Yuki,Sano ^[1] ; Hinako,Tanaka ^[1] ; Nicole L,Butler ^[2] ; Takeshi,Ito ^[2] ; Tatsuhiko,Tosaki ^[1] ; Joel E,Morgan ^[3] ; Masatoshi,Murai ^[1] ; Blanca,Barquera ^[4] ; Hideto,Miyoshi ^[5]

作者单位： Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan. ^[1] Department of Biological Science and. ^[2] Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA. ^[3] Department of Biological Science and.;Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA. ^[4] Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kyoto, Japan miyoshi@kais.kyoto-u.ac.jp. ^[5]

关键词 Na+-pumping NADH-ubiquinone oxidoreductase (Na+-NQR)aurachin chemical biology enzyme inhibitor korormicin photoaffinity labeling respiratory chain respiratory enzyme ubiquinone

主题词细菌蛋白质类(Bacterial Proteins);NADH, NADPH氧化还原酶类(NADH, NADPH Oxidoreductases);泛醌(Ubiquinone);霍乱弧菌(Vibrio cholerae)

DOI 10.1074/jbc.RA120.014229

PMID 32690607

发布时间 2021-09-05

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准确一般字义偏差语意偏离译文作用小提交