Myeloid Cell-Intrinsic IRF5 Promotes T Cell Responses through Multiple Distinct Checkpoints In Vivo, and <i>IRF5</i> Immune-Mediated Disease Risk Variants Modulate These Myeloid Cell Functions.
第一作者:
Jie,Yan
第一单位:
Department of Internal Medicine, Yale University, New Haven, CT 06520.
作者:
主题词
动物(Animals);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);细胞因子类(Cytokines);树突细胞(Dendritic Cells);基因表达调控(Gene Expression Regulation);人类(Humans);干扰素调节因子类(Interferon Regulatory Factors);淋巴结(Lymph Nodes);淋巴细胞活化(Lymphocyte Activation);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 近交C57BL(Mice, Inbred C57BL);单核细胞(Monocytes);髓系细胞(Myeloid Cells);受体, 模式识别(Receptors, Pattern Recognition);信号传导(Signal Transduction);T淋巴细胞(T-Lymphocytes);增量调节(Up-Regulation)
DOI
10.4049/jimmunol.1900743
PMID
32690658
发布时间
2021-12-08
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Journal of immunology (Baltimore, Md.
1024-1038页
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