A six-gene expression signature related to angiolymphatic invasion is associated with poor survival in laryngeal squamous cell carcinoma.

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作者： Karl,Metzger ^[1] ; Julius,Moratin ^[2] ; Kolja,Freier ^[3] ; Jürgen,Hoffmann ^[2] ; Karim,Zaoui ^[4] ; Michaela,Plath ^[4] ; Fabian,Stögbauer ^[5] ; Christian,Freudlsperger ^[2] ; Jochen,Hess ^[6] ; Dominik,Horn ^[3]

作者单位： Department of Oral and Cranio-Maxillofacial Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. karl.metzger@med.uni-heidelberg.de. ^[1] Department of Oral and Cranio-Maxillofacial Surgery, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. ^[2] Department of Oral and Cranio-Maxillofacial Surgery, Saarland University Hospital, Kirrberger Str. 100, 66421, Homburg, Germany. ^[3] Department of Otorhinolaryngology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. ^[4] Institute of Pathology, Technical University of Munich, TUM School of Medicine, Trogerstr. 18, 81675, Munich, Germany. ^[5] Department of Otorhinolaryngology, Section Experimental and Translational Head and Neck Oncology, Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. ^[6]

关键词 Angiolymphatic invasion HNSCC Head and neck cancer Head and neck squamous cell carcinoma Laryngeal squamous cell carcinoma

主题词基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);头颈部肿瘤(Head and Neck Neoplasms);人类(Humans);肿瘤复发, 局部(Neoplasm Recurrence, Local);预后(Prognosis)

DOI 10.1007/s00405-020-06214-1

PMID 32691230

发布时间 2022-02-18

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