RNA editing mediates the functional switch of COPA in a novel mechanism of hepatocarcinogenesis.

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作者： Yangyang,Song ^[1] ; Omer,An ^[1] ; Xi,Ren ^[2] ; Tim Hon Man,Chan ^[3] ; Daryl Jin Tai,Tay ^[1] ; Sze Jing,Tang ^[1] ; Jian,Han ^[1] ; HuiQi,Hong ^[4] ; Vanessa Hui En,Ng ^[1] ; Xinyu,Ke ^[5] ; Haoqing,Shen ^[1] ; Priyankaa,Pitcheshwar ^[1] ; Jaymie Siqi,Lin ^[1] ; Ka Wai,Leong ^[1] ; Fernando Bellido,Molias ^[1] ; Henry,Yang ^[1] ; Dennis,Kappei ^[2] ; Leilei,Chen ^[6]

作者单位： Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore. ^[1] Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore. ^[2] Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Laboratory Medicine, Molecular Diagnosis Centre, National University Health System, Singapore 119074, Singapore. ^[3] Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117549, Singapore. ^[4] Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594, Singapore. ^[5] Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore; Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117594, Singapore. Electronic address: polly_chen@nus.edu.sg. ^[6]

关键词 A-to-I ADARs COPA HCC Protein recoding RNA editing