首页> Cell> Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus.

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus.

导出 OA

翻译打印收藏纠错

第一作者： Bette,Korber

第一单位： Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA; New Mexico Consortium, Los Alamos, NM 87545, USA. Electronic address: btk@lanl.gov.

作者： Bette,Korber ^[1] ; Will M,Fischer ^[2] ; Sandrasegaram,Gnanakaran ^[2] ; Hyejin,Yoon ^[2] ; James,Theiler ^[2] ; Werner,Abfalterer ^[2] ; Nick,Hengartner ^[2] ; Elena E,Giorgi ^[2] ; Tanmoy,Bhattacharya ^[2] ; Brian,Foley ^[2] ; Kathryn M,Hastie ^[3] ; Matthew D,Parker ^[4] ; David G,Partridge ^[5] ; Cariad M,Evans ^[5] ; Timothy M,Freeman ^[4] ; Thushan I,de Silva ^[6] ; Sheffield COVID-19 Genomics Group ^[7] ; Charlene,McDanal ^[7] ; Lautaro G,Perez ^[7] ; Haili,Tang ^[8] ; Alex,Moon-Walker ^[9] ; Sean P,Whelan ^[7] ; Celia C,LaBranche ^[3] ; Erica O,Saphire ^[7] ; David C,Montefiori

作者单位： Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA; New Mexico Consortium, Los Alamos, NM 87545, USA. Electronic address: btk@lanl.gov. ^[1] Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM 87545, USA. ^[2] La Jolla Institute for Immunology, La Jolla, CA 92037, USA. ^[3] Sheffield Biomedical Research Centre & Sheffield Bioinformatics Core, University of Sheffield, Sheffield S10 2HQ, UK. ^[4] Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK. ^[5] Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK; Department of Infection, Immunity and Cardiovascular Disease, Medical School, University of Sheffield, Sheffield S10 2RX, UK. ^[6] Duke Human Vaccine Institute & Department of Surgery, Durham, NC 27710, USA. ^[7] La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Program in Virology, Harvard University, Boston, MA 02115, USA; Department of Molecular Microbiology, Washington University in Saint Louis, St. Louis, MO 63130, USA. ^[8] Department of Molecular Microbiology, Washington University in Saint Louis, St. Louis, MO 63130, USA. ^[9]

关键词 COVID-19 PCR cycle threshold SARS-CoV-2 Spike antibody diversity evolution infectivity neutralization pseudovirus