Novel cyclometalated Ru(II) complexes containing isoquinoline ligands: Synthesis, characterization, cellular uptake and in vitro cytotoxicity.

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作者： Jincan,Chen ^[1] ; Jie,Wang ^[1] ; Yuanyuan,Deng ^[1] ; Baojun,Li ^[1] ; Chengpeng,Li ^[2] ; Yuxue,Lin ^[1] ; Dongbin,Yang ^[3] ; Huanyun,Zhang ^[3] ; Lanmei,Chen ^[4] ; Tao,Wang ^[5]

作者单位： Guangdong Key Laboratory for Research and Development of Nature Drugs, Marine Biomedical Research Institute, School of Pharmacy, Guangdong Medical University, Zhanjiang, 524023, China. ^[1] The Public Service Platform of South China Sea for R&D Marine Biomedicine Resources, Marine Biomedical Research Institute, Guangdong Medical University, Zhanjiang, 524023, China. ^[2] The Affiliated People's Hospital of Hebi of Henan University, Hebi, 456030, China. ^[3] Guangdong Key Laboratory for Research and Development of Nature Drugs, Marine Biomedical Research Institute, School of Pharmacy, Guangdong Medical University, Zhanjiang, 524023, China. Electronic address: lanmeichen@126.com. ^[4] The College of Nursing and Health, Zhengzhou University, Zhengzhou, 450001, China; Centre for Comparative Genomics, Murdoch University, Perth, WA, 6150, Australia. Electronic address: Tao.Wang@murdoch.edu.au. ^[5]

关键词 Apoptosis Cyclometalated Ru(II) complexes DNA damage Isoquinoline Low toxicity