首页> Journal of chromatography. A> From batch to continuous chromatographic purification of a therapeutic peptide through multicolumn countercurrent solvent gradient purification.

From batch to continuous chromatographic purification of a therapeutic peptide through multicolumn countercurrent solvent gradient purification.

导出 LinkOut

翻译打印收藏纠错

第一作者： Chiara De,Luca

第一单位： Dept. of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy.

作者： Chiara De,Luca ^[1] ; Simona,Felletti ^[1] ; Giulio,Lievore ^[1] ; Alessandro,Buratti ^[1] ; Sebastian,Vogg ^[2] ; Massimo,Morbidelli ^[2] ; Alberto,Cavazzini ^[1] ; Martina,Catani ^[3] ; Marco,Macis ^[4] ; Antonio,Ricci ^[5] ; Walter,Cabri ^[6]

作者单位： Dept. of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. ^[1] Institute for Chemical and Bioengineering, ETH Zurich, Vladimir-Prelog-Weg 1, 8093 Zurich, Switzerland. ^[2] Dept. of Chemistry and Pharmaceutical Sciences, University of Ferrara, via L. Borsari 46, 44121 Ferrara, Italy. Electronic address: ctnmtn@unife.it. ^[3] Fresenius Kabi iPSUM, via San Leonardo 23, 45010, Villadose, Rovigo, Italy. ^[4] Fresenius Kabi iPSUM, via San Leonardo 23, 45010, Villadose, Rovigo, Italy. Electronic address: Antonio.Ricci@fresenius-kabi.com. ^[5] Fresenius Kabi iPSUM, via San Leonardo 23, 45010, Villadose, Rovigo, Italy; Department of Chemistry "G. Ciamician", University of Bologna, via Selmi 2, 40126, Bologna, Italy. ^[6]

关键词 Continuous chromatography Multicolumn countercurrent solvent gradient process Peptide purification Preparative chromatography

医学主题词色谱法, 高压液相(Chromatography, High Pressure Liquid);反流分布法(Countercurrent Distribution);胰高血糖素(Glucagon);肽类(Peptides);溶剂(Solvents);时间因素(Time Factors)

DOI 10.1016/j.chroma.2020.461304

PMID 32709347

发布时间 2020-09-02

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交