首页> Lancet (London, England)> Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.

Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial.

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第一作者： Kenneth H,Mayer

第一单位： The Fenway Institute, Fenway Health, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.

作者： Kenneth H,Mayer ^[1] ; Jean-Michel,Molina ^[2] ; Melanie A,Thompson ^[3] ; Peter L,Anderson ^[4] ; Karam C,Mounzer ^[5] ; Joss J,De Wet ^[6] ; Edwin,DeJesus ^[7] ; Heiko,Jessen ^[8] ; Robert M,Grant ^[9] ; Peter J,Ruane ^[10] ; Pamela,Wong ^[11] ; Ramin,Ebrahimi ^[11] ; Lijie,Zhong ^[11] ; Anita,Mathias ^[12] ; Christian,Callebaut ^[13] ; Sean E,Collins ^[14] ; Moupali,Das ^[15] ; Scott,McCallister ^[14] ; Diana M,Brainard ^[14] ; Cynthia,Brinson ^[16] ; Amanda,Clarke ^[17] ; Pep,Coll ^[18] ; Frank A,Post ^[19] ; C Bradley,Hare ^[20]

作者单位： The Fenway Institute, Fenway Health, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA. ^[1] Infectious Diseases Department, Hopitaux Saint-Louis Lariboisière, University of Paris and INSERM U944, Paris, France. ^[2] AIDS Research Consortium of Atlanta, Atlanta, GA, USA. ^[3] Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA. ^[4] Philadelphia FIGHT, Philadelphia, PA, USA. ^[5] Spectrum Health, Vancouver, BC, Canada. ^[6] Orlando Immunology Center, Orlando, FL, USA. ^[7] Praxis Jessen(2) + Kollegen, Berlin, Germany. ^[8] San Francisco AIDS Foundation, and University of California, San Francisco, CA, USA. ^[9] Ruane Medical and Liver Health Institute, Los Angeles, CA, USA. ^[10] Department of Biometrics, Gilead Sciences, Foster City, CA, USA. ^[11] Department of Clinical Pharmacology, Gilead Sciences, Foster City, CA, USA. ^[12] Department of Virology, Gilead Sciences, Foster City, CA, USA. ^[13] Department of HIV and Emerging Viral Infections Clinical Research, Gilead Sciences, Foster City, CA, USA. ^[14] Department of HIV and Emerging Viral Infections Clinical Research, Gilead Sciences, Foster City, CA, USA. Electronic address: moupali.as@gilead.com. ^[15] Central Texas Clinical Research, Austin, TX, USA. ^[16] Royal Sussex County Hospital, Brighton and Sussex University Hospitals National Health Service (NHS) Trust, Brighton, UK. ^[17] BCN Checkpoint and IrsiCaixa-AIDS Research Institute, Barcelona, Spain. ^[18] King's College Hospital NHS Foundation Trust, King's College Hospital, London, UK. ^[19] Department of Adult and Family Medicine, Kaiser Permanente San Francisco Medical Center, San Francisco, CA, USA. ^[20]