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Transient Dux expression facilitates nuclear transfer and induced pluripotent stem cell reprogramming.

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第一作者： Lei,Yang

第一单位： State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, Hohhot, China.

作者： Lei,Yang ^[1] ; Xuefei,Liu ^[1] ; Lishuang,Song ^[2] ; Anqi,Di ^[2] ; Guanghua,Su ^[2] ; Chunling,Bai ^[2] ; Zhuying,Wei ^[2] ; Guangpeng,Li ^[2]

作者单位： State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, Hohhot, China. ^[1] State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock (R2BGL), Inner Mongolia University, Hohhot, China.;Research Center for Mammalian Reproductive Biology and Biotechnology, College of Life Sciences, Inner Mongolia University, Hohhot, China. ^[2]

关键词 Dppa2/4 Dux SCNT chemically induced pluripotent stem cells zygotic genome activation

医学主题词动物(Animals);胚泡(Blastocyst);胚胎, 哺乳动物(Embryo, Mammalian);胚胎发育(Embryonic Development);基因组(Genome);诱导多能干细胞(Induced Pluripotent Stem Cells);小鼠(Mice);核蛋白质类(Nuclear Proteins);核移植技术(Nuclear Transfer Techniques);转录因子(Transcription Factors);合子(Zygote)

DOI 10.15252/embr.202050054

PMID 32715614

发布时间 2026-04-24

基金项目

2016ZX08007-002/Genetically Modified Organisms Breeding Major Projects/International State Key Laboratory of R2BGL/International Inner Mongolia University Chief Scientist Program/International Inner Mongolia Autonomous Region Basic Research Project/International

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