Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

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第一作者： Jiaping,Li

第一单位： Department of Interventional Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangdong, China.

作者： Jiaping,Li ^[1] ; Wei,Jiang ^[2] ; Jinwang,Wei ^[3] ; Jianwei,Zhang ^[4] ; Linbo,Cai ^[5] ; Minjie,Luo ^[6] ; Zhan,Wang ^[7] ; Wending,Sun ^[3] ; Shengzhou,Wang ^[3] ; Chen,Wang ^[3] ; Chun,Dai ^[3] ; Jun,Liu ^[3] ; Guan,Wang ^[3] ; Jiping,Wang ^[8] ; Qiang,Xu ^[9] ; Yanhong,Deng ^[10]

作者单位： Department of Interventional Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangdong, China. ^[1] Department of Radiation Oncology, Huanhu Hospital, Tianjin, China. ^[2] GenomiCare Biotechnology Co. Ltd, Shanghai, China. ^[3] Department of Medical Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, No. 26 Erheng Road, Tianhe District, Guangzhou, 510655, China. ^[4] Department of Oncology, Guangdong 999 Brain Hospital, Guangdong, China. ^[5] Department of Pediatric Neurosurgery, Zhujiang Hospital of Southern Medical University, Guangdong, China. ^[6] Department of Medical Oncology, Changzheng Hospital, The Second Military Medical University, Shanghai, China. ^[7] Division of Surgical Oncology, Brigham and Women's Hospital, Boston, MA, USA. ^[8] GenomiCare Biotechnology Co. Ltd, Shanghai, China. qiang.xu@genomicarebio.com. ^[9] Department of Medical Oncology, The Sixth Affiliated Hospital of Sun Yat-sen University, No. 26 Erheng Road, Tianhe District, Guangzhou, 510655, China. dengyanh@mail.sysu.edu.cn. ^[10]

关键词 Cancer treatment response Customized ctDNA panel Drug-related mutation Whole?exome sequencing ctDNA fingerprint

主题词 DNA, 肿瘤(DNA, Neoplasm);基因, 肿瘤(Genes, Neoplasm);人类(Humans);突变(Mutation);肿瘤复发, 局部(Neoplasm Recurrence, Local);肿瘤(Neoplasms)

DOI 10.1186/s12967-020-02449-y

PMID 32738923

发布时间 2024-03-29

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准确一般字义偏差语意偏离译文作用小提交