DNA demethylation overcomes attenuation of colchicine biosynthesis in an endophytic fungus Diaporthe.

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第一作者： Vishwanath Bhat,Deepika

第一单位： Department of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: deepikamlsc@gmail.com.

作者： Vishwanath Bhat,Deepika ^[1] ; Manik,Vohra ^[2] ; Sumit,Mishra ^[3] ; Kavita,Dorai ^[4] ; Padmalatha,Rai ^[5] ; Kapaettu,Satyamoorthy ^[6] ; Thokur Sreepathy,Murali ^[7]

作者单位： Department of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: deepikamlsc@gmail.com. ^[1] Department of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: manik99vohra@gmail.com. ^[2] Department of Physical Sciences, Indian Institute of Science Education & Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli PO, 140306 Punjab, India. Electronic address: sumitmishra@iisermohali.ac.in. ^[3] Department of Physical Sciences, Indian Institute of Science Education & Research (IISER) Mohali, Sector 81, SAS Nagar, Manauli PO, 140306 Punjab, India. Electronic address: kdorai@gmail.com. ^[4] Department of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: padmalatha.rai@manipal.edu. ^[5] Department of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: ksatyamoorthy@manipal.edu. ^[6] Department of Biotechnology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, India. Electronic address: murali.ts@manipal.edu. ^[7]

关键词 5-azacytidine Attenuation Colchicine Endophyte Epigenetic modifiers Gloriosa superba

主题词子囊菌纲(Ascomycota);阿扎胞苷(Azacitidine);秋水仙碱(Colchicine);表观基因组学(Epigenomics);磁共振波谱学(Magnetic Resonance Spectroscopy)

DOI 10.1016/j.jbiotec.2020.07.019

PMID 32745507

发布时间 2024-02-29

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