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Rational discovery of molecular glue degraders via scalable chemical profiling.

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第一作者： Cristina,Mayor-Ruiz

第一单位： CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

作者： Cristina,Mayor-Ruiz ^[1] ; Sophie,Bauer ^[1] ; Matthias,Brand ^[1] ; Zuzanna,Kozicka ^[2] ; Marton,Siklos ^[1] ; Hana,Imrichova ^[1] ; Ines H,Kaltheuner ^[3] ; Elisa,Hahn ^[1] ; Kristina,Seiler ^[1] ; Anna,Koren ^[1] ; Georg,Petzold ^[4] ; Michaela,Fellner ^[5] ; Christoph,Bock ^[6] ; André C,Müller ^[1] ; Johannes,Zuber ^[5] ; Matthias,Geyer ^[3] ; Nicolas H,Thomä ^[4] ; Stefan,Kubicek ^[1] ; Georg E,Winter ^[7]

作者单位： CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. ^[1] FMI Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.;Faculty of Science, University of Basel, Basel, Switzerland. ^[2] Institute of Structural Biology, University of Bonn, Bonn, Germany. ^[3] FMI Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland. ^[4] Research Institute of Molecular Pathology, Vienna BioCenter, Vienna, Austria. ^[5] CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.;Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria. ^[6] CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. gwinter@cemm.oeaw.ac.at. ^[7]