DNA Mismatch Repair Gene Variants in Sporadic Solid Cancers.

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第一作者： Fabian,Caja

第一单位： Department of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.;Department of Cell Biology, Faculty of Science, Charles University, 12000 Prague, Czech Republic.

作者： Fabian,Caja ^[1] ; Ludmila,Vodickova ^[2] ; Jan,Kral ^[3] ; Veronika,Vymetalkova ^[2] ; Alessio,Naccarati ^[4] ; Pavel,Vodicka ^[2]

作者单位： Department of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.;Department of Cell Biology, Faculty of Science, Charles University, 12000 Prague, Czech Republic. ^[1] Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, 14220 Prague, Czech Republic.;Institute of Biology and Medical Genetics, 1st Medical Faculty, Charles University, 12000 Prague, Czech Republic.;Biomedical Centre, Faculty of Medicine in Pilsen, Charles University in Prague, 32300 Pilsen, Czech Republic. ^[2] Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, 14220 Prague, Czech Republic.;Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, 14200 Prague, Czech Republic. ^[3] Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, 14220 Prague, Czech Republic.;Italian Institute for Genomic Medicine (IIGM), 10060 Torino, Italy. ^[4]

关键词 cancer genes genetic variants genotype mismatch repair patients single nucleotide polymorphism treatment outcome