Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.

导出 LinkOut

翻译打印收藏纠错

第一作者： Salvador F,Ausar

第一单位： Bioprocess Research and Development, Sanofi Pasteur Ltd., Toronto, ON, M2R 3T4, Canada.

作者： Salvador F,Ausar ^[1] ; Shaolong,Zhu ^[2] ; Jessica,Duprez ^[3] ; Michael,Cohen ^[4] ; Thomas,Bertrand ^[5] ; Valérie,Steier ^[5] ; Derek J,Wilson ^[6] ; Stephen,Li ^[7] ; Anthony,Sheung ^[1] ; Roger H,Brookes ^[1] ; Artur,Pedyczak ^[3] ; Alexey,Rak ^[5] ; D,Andrew James ^[8]

作者单位： Bioprocess Research and Development, Sanofi Pasteur Ltd., Toronto, ON, M2R 3T4, Canada. ^[1] Analytical Sciences, Sanofi Pasteur Ltd., Toronto, ON, M2R 3T4, Canada.;Center for Research in Mass Spectrometry, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada. ^[2] Analytical Sciences, Sanofi Pasteur Ltd., Toronto, ON, M2R 3T4, Canada. ^[3] Center for Research in Mass Spectrometry, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada.;Fluidigm Corporation, Markham, ON, L3R 4G5, Canada. ^[4] Research Platform, Sanofi R&D, Vitry-sur-Seine, 94400, Paris, France. ^[5] Center for Research in Mass Spectrometry, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada. ^[6] Fluidigm Corporation, Markham, ON, L3R 4G5, Canada. ^[7] Analytical Sciences, Sanofi Pasteur Ltd., Toronto, ON, M2R 3T4, Canada. Andrew.James@sanofi.com.;Center for Research in Mass Spectrometry, Department of Chemistry, York University, Toronto, ON, M3J 1P3, Canada. Andrew.James@sanofi.com. ^[8]

主题词动物(Animals);百日咳博德特菌(Bordetella pertussis);CHO细胞(CHO Cells);仓鼠亚科(Cricetinae);仓鼠属(Cricetulus);结晶学, X线(Crystallography, X-Ray);氘交换测定(Deuterium Exchange Measurement);人类(Humans);百白咳毒素(Pertussis Toxin);百日咳菌苗(Pertussis Vaccine);蛋白质构象(Protein Conformation);类毒素类(Toxoids);百日咳(Whooping Cough)

DOI 10.1038/s42003-020-01153-3

PMID 32759959

发布时间 2024-07-31

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览0

Communications biology

2020年3卷1期

427页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.

Communications biology

相似文献

Communications biology

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.

Communications biology

相似文献

Communications biology

相关期刊

检索历史清除