Optimization of Methods for the Production and Refolding of Biologically Active Disulfide Bond-Rich Antibody Fragments in Microbial Hosts.

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作者： Bhupal,Ban ^[1] ; Maya,Sharma ^[2] ; Jagathpala,Shetty ^[3]

作者单位： Antibody Engineering and Technology Core, University of Virginia, Charlottesville, VA 22904, USA. ^[1] Department of Cell Biology, University of Virginia, Charlottesville, VA 22904, USA. ^[2] Pharmaceutical Biotechnology Center, Indiana Biosciences Research Institutes (IBRI), Indianapolis, IN 46202, USA. ^[3] Department of Data Science, School of Informatics and Computing Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, IN 46202, USA. ^[4] Department of Biomedical Engineering, University of Virginia, Charlottesville, VA 22904, USA. ^[5]

关键词 disulfide bonds inclusion bodies recombinant antibodies redox pair refolding

DOI 10.3390/antib9030039

PMID 32764309

发布时间 2024-03-29

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Antibodies (Basel, Switzerland)

2020年9卷3期

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Optimization of Methods for the Production and Refolding of Biologically Active Disulfide Bond-Rich Antibody Fragments in Microbial Hosts.

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Antibodies (Basel, Switzerland)

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Optimization of Methods for the Production and Refolding of Biologically Active Disulfide Bond-Rich Antibody Fragments in Microbial Hosts.

Antibodies (Basel, Switzerland)

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Antibodies (Basel, Switzerland)

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