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TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis.

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第一作者: Francesca,Cignarella
第一单位: Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA.;Alector, 131 Oyster Point Blvd #600, South San Francisco, CA, 94080, USA.
作者单位: Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA.;Alector, 131 Oyster Point Blvd #600, South San Francisco, CA, 94080, USA. [1] Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA.;Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele - Milan, 20090, Italy. [2] Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA. [3] Alector, 131 Oyster Point Blvd #600, South San Francisco, CA, 94080, USA. [4] Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA.;Department of Anesthesiology, First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China. [5] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA.;Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, 63110, USA.;NeuroGenomics and Informatics, Washington University School of Medicine, St. Louis, MO, 63110, USA. [6] ARGO Open Lab Platform for Genome sequencing, AREA Science Park, Padriciano 99, 34149, Trieste, Italy. [7] Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, 63110, USA.;NeuroGenomics and Informatics, Washington University School of Medicine, St. Louis, MO, 63110, USA. [8] Brain and Mind Centre, University of Sydney, 94 Mallett St Camperdown, Sydney, NSW, 2050, Australia. [9] Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA.;Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO, 63110, USA. [10] Alector, 131 Oyster Point Blvd #600, South San Francisco, CA, 94080, USA. Ilaria.tassi@alector.com. [11] Department of Neurology, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO, 63110, USA. picciol@wustl.edu.;NeuroGenomics and Informatics, Washington University School of Medicine, St. Louis, MO, 63110, USA. picciol@wustl.edu.;Brain and Mind Centre, University of Sydney, 94 Mallett St Camperdown, Sydney, NSW, 2050, Australia. picciol@wustl.edu. [12]
DOI 10.1007/s00401-020-02193-z
PMID 32772264
发布时间 2024-04-29
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