O-linked mucin-type glycosylation regulates the transcriptional programme downstream of EGFR.

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第一作者： Virginia,Tajadura-Ortega

第一单位： Breast Cancer Biology Lab, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9RT, UK.;Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, UK.

作者： Virginia,Tajadura-Ortega ^[1] ; Gennaro,Gambardella ^[2] ; Alexandra,Skinner ^[3] ; Adnan,Halim ^[4] ; Julie,Van Coillie ^[4] ; Katrine Ter-Borch Gram,Schjoldager ^[4] ; Richard,Beatson ^[3] ; Rosalind,Graham ^[3] ; Daniela,Achkova ^[5] ; Joyce,Taylor-Papadimitriou ^[3] ; Francesca D,Ciccarelli ^[6] ; Joy M,Burchell ^[3]

作者单位： Breast Cancer Biology Lab, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9RT, UK.;Glycosciences Laboratory, Department of Metabolism, Digestion and Reproduction, Imperial College London, Burlington Danes Building, Du Cane Road, London W12 0NN, UK. ^[1] Department of Chemical Materials and Industrial Engineering, University of Naples Federico II, 1-80125 Naples, Italy.;Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy. ^[2] Breast Cancer Biology Lab, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9RT, UK. ^[3] Functional and Cellular Glycobiology, Glycomics Programme, University of Copenhagen, Copenhagen DK-2200, Denmark. ^[4] CAR Mechanics Lab, School of Cancer & Pharmaceutical Sciences, King's College London, London SE1 9RT, UK.;Autolus Ltd. Forest House, 58 Wood Ln, White City, London W12 7RZ, UK. ^[5] Cancer Systems Biology Laboratory, Francis Crick Institute, London NW1 1AT, UK.;CRUK King's Health Partner Centre, King's College London, London SE1 9RT, UK. ^[6]

关键词 EGFR Galectin-3 MUC1 O-linked glycosylation transcription

主题词乳腺肿瘤(Breast Neoplasms);女(雌)性(Female);糖基化(Glycosylation);人类(Humans);黏蛋白-1(Mucin-1);受体, 雌激素(Receptors, Estrogen)

DOI 10.1093/glycob/cwaa075

PMID 32776095

发布时间 2024-02-10

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