Reduced Chronic Toxicity and Carcinogenicity in A/J Mice in Response to Life-Time Exposure to Aerosol From a Heated Tobacco Product Compared With Cigarette Smoke.

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第一作者： Ee Tsin,Wong

第一单位： PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore 117406, Singapore.

作者： Ee Tsin,Wong ^[1] ; Karsta,Luettich ^[2] ; Subash,Krishnan ^[1] ; Sin Kei,Wong ^[1] ; Wei Ting,Lim ^[1] ; Demetrius,Yeo ^[1] ; Ansgar,Büttner ^[3] ; Patrice,Leroy ^[1] ; Grégory,Vuillaume ^[1] ; Stéphanie,Boué ^[1] ; Julia,Hoeng ^[1] ; Patrick,Vanscheeuwijck ^[1] ; Manuel C,Peitsch ^[1]

作者单位： PMI R&D, Philip Morris International Research Laboratories Pte. Ltd, Science Park II, Singapore 117406, Singapore. ^[1] Department of Life Sciences, Systems Toxicology, PMI R&D, Philip Morris Products S.A, CH-2000 Neuchâtel, Switzerland. ^[2] Histovia GmbH, 51491 Overath, Germany. ^[3]

关键词 carcinogenicity chronic toxicity cigarette smoke heated tobacco product inhalation mouse

主题词气雾剂(Aerosols);动物(Animals);男(雄)性(Male);小鼠(Mice);小鼠, 近交系(Mice, Inbred Strains);烟(Smoke);吸烟(Smoking)

DOI 10.1093/toxsci/kfaa131

PMID 32780830

发布时间 2021-08-11

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