The genetic architecture of human brainstem structures and their involvement in common brain disorders.
第一作者:
Torbjørn,Elvsåshagen
第一单位:
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.;Department of Neurology, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.
作者:
Torbjørn,Elvsåshagen [1]
;
Shahram,Bahrami [2]
;
Dennis,van der Meer [3]
;
Ingrid,Agartz [4]
;
Dag,Alnæs [5]
;
Deanna M,Barch [6]
;
Ramona,Baur-Streubel [7]
;
Alessandro,Bertolino [8]
;
Mona K,Beyer [9]
;
Giuseppe,Blasi [8]
;
Stefan,Borgwardt [10]
;
Birgitte,Boye [11]
;
Jan,Buitelaar [12]
;
Erlend,Bøen [13]
;
Elisabeth Gulowsen,Celius [14]
;
Simon,Cervenka [15]
;
Annette,Conzelmann [16]
;
David,Coynel [17]
;
Pasquale,Di Carlo [18]
;
Srdjan,Djurovic [19]
;
Sarah,Eisenacher [20]
;
Thomas,Espeseth [21]
;
Helena,Fatouros-Bergman [15]
;
Lena,Flyckt [15]
;
Barbara,Franke [22]
;
Oleksandr,Frei [5]
;
Barbara,Gelao [23]
;
Hanne Flinstad,Harbo [14]
;
Catharina A,Hartman [24]
;
Asta,Håberg [25]
;
Dirk,Heslenfeld [26]
;
Pieter J,Hoekstra [27]
;
Einar A,Høgestøl [14]
;
Rune,Jonassen [28]
;
Erik G,Jönsson [29]
;
Karolinska Schizophrenia Project (KaSP) consortium [30]
;
Peter,Kirsch [31]
;
Iwona,Kłoszewska [5]
;
Trine Vik,Lagerberg [32]
;
Nils Inge,Landrø [33]
;
Stephanie,Le Hellard [34]
;
Klaus-Peter,Lesch [35]
;
Luigi A,Maglanoc [36]
;
Ulrik F,Malt [37]
;
Patrizia,Mecocci [38]
;
Ingrid,Melle [39]
;
Andreas,Meyer-Lindenberg [35]
;
Torgeir,Moberget [40]
;
Jan Egil,Nordvik [41]
;
Lars,Nyberg [5]
;
Kevin S O',Connell [42]
;
Jaap,Oosterlaan [18]
;
Marco,Papalino [43]
;
Andreas,Papassotiropoulos [7]
;
Paul,Pauli [18]
;
Giulio,Pergola [44]
;
Karin,Persson [45]
;
Dominique,de Quervain [46]
;
Andreas,Reif [35]
;
Jaroslav,Rokicki [47]
;
Daan,van Rooij [38]
;
Alexey A,Shadrin [48]
;
André,Schmidt [39]
;
Emanuel,Schwarz [49]
;
Geir,Selbæk [50]
;
Hilkka,Soininen [51]
;
Piotr,Sowa [52]
;
Vidar M,Steen [53]
;
Magda,Tsolaki [54]
;
Bruno,Vellas [55]
;
Lei,Wang [56]
;
Eric,Westman [57]
;
Georg C,Ziegler [58]
;
Mathias,Zink [38]
;
Ole A,Andreassen [35]
;
Lars T,Westlye [59]
;
Tobias,Kaufmann
作者单位:
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.;Department of Neurology, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway. torbjorn.elvsashagen@medisin.uio.no.
[1]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. shahram.bahrami@medisin.uio.no.
[2]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
[3]
Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.;Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.;NORMENT, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[4]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
[5]
Departments of Psychological & Brain Sciences, Psychiatry, and Radiology, Washington University in St. Louis, St. Louis, USA.
[6]
Department of Psychology I and Centre of Mental Health, University of Würzburg, Würzburg, Germany.
[7]
Institute of Psychiatry, University of Bari, Bari, Italy.;Department of Basic Medical Science, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
[8]
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
[9]
Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.;Institute of Psychiatry, King's College, London, UK.;Department of Psychiatry and Psychotherapy, University of Lübeck, Lübeck, Germany.
[10]
Psychosomatic and CL Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Department of Behavioural Sciences in Medicine, University of Oslo, Oslo, Norway.
[11]
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.;Karakter Child and Adolescent Psychiatry University Centre, Nijmegen, The Netherlands.
[12]
Psychosomatic and CL Psychiatry, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
[13]
Department of Neurology, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[14]
Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.
[15]
Children and Adolescence Psychiatry, University of Tübingen, Tübingen, Germany.
[16]
Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, CH-4055, Basel, Switzerland.;Division of Cognitive Neuroscience, Department of Psychology, University of Basel, CH-4055 Basel, Switzerland.
[17]
Department of Basic Medical Science, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.
[18]
Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.;NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
[19]
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.;Institute of Psychiatric and Psychosomatic Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
[20]
Department of Psychology, University of Oslo, Oslo, Norway.;Bjørknes College, Lovisenberggata, 13, 0456, Oslo, Norway.
[21]
Departments of Human Genetics and Psychiatry, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
[22]
Institute of Psychiatry, University of Bari, Bari, Italy.
[23]
Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
[24]
Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.;Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim, Norway.
[25]
Clinical Neuropsychology section, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.;Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
[26]
Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
[27]
Department of Psychology, University of Oslo, Oslo, Norway.;Faculty of Health Sciences, Oslo Metropolitan University, Oslo, Norway.
[28]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Care Services, Stockholm Region, Stockholm, Sweden.
[29]
Department of Clinical Psychology, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.;Bernstein Center for Computational Neuroscience Heidelberg/Mannheim, Mannheim, Germany.
[30]
Department of Old Age Psychiatry and Psychotic Disorders, Medical University of Lodz, Lodz, Poland.
[31]
Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.;Department of Psychology, University of Oslo, Oslo, Norway.
[32]
NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.
[33]
Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.;Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.;Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
[34]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Department of Psychology, University of Oslo, Oslo, Norway.
[35]
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[36]
Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
[37]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
[38]
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
[39]
The CatoSenteret Rehabilitation Center, Son, Norway.
[40]
Departments of Radiation Sciences and Integrative Medical Biology, Umeå Center for Functional Brain Imaging, Umeå University, Umeå, Sweden.
[41]
Clinical Neuropsychology section, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.;Emma Children's Hospital Amsterdam UMC, University of Amsterdam, Emma Neuroscience Group, Department of Pediatrics, Amsterdam Reproduction & Development, Amsterdam, The Netherlands.
[42]
Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, CH-4055, Basel, Switzerland.;Division of Cognitive Neuroscience, Department of Psychology, University of Basel, CH-4055 Basel, Switzerland.;Psychiatric University Clinics, University of Basel, Basel, Switzerland.;Department Biozentrum, Life Sciences Training Facility, University of Basel, Basel, Switzerland.
[43]
Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.;Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.
[44]
Transfaculty Research Platform Molecular and Cognitive Neurosciences, University of Basel, CH-4055, Basel, Switzerland.;Division of Cognitive Neuroscience, Department of Psychology, University of Basel, CH-4055 Basel, Switzerland.;Psychiatric University Clinics, University of Basel, Basel, Switzerland.
[45]
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany.
[46]
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.
[47]
Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
[48]
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.;Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.;Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway.
[49]
Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.;Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland.
[50]
Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.
[51]
NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway.;Dr. E. Martens Research Group for Biological Psychiatry, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.
[52]
1st University Department of Neurology, Aristotle University of Thessaloniki, Makedonia, Greece.
[53]
INSERM U 1027, University of Toulouse, Toulouse, France.
[54]
Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
[55]
Institute of Psychiatry, King's College, London, UK.;Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden.
[56]
Division of Molecular Psychiatry, Center of Mental Health, University of Würzburg, Würzburg, Germany.
[57]
Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.;District hospital Mittelfranken, Ansbach, Germany.
[58]
NORMENT, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway. tobias.kaufmann@medisin.uio.no.;Institute of Clinical Medicine, University of Oslo, Oslo, Norway. tobias.kaufmann@medisin.uio.no.
[59]
医学主题词
脑疾病(Brain Diseases);脑干(Brain Stem);基因, 重叠(Genes, Overlapping);基因座(Genetic Loci);全基因组关联研究(Genome-Wide Association Study);人类(Humans);磁共振成像(Magnetic Resonance Imaging);多因子遗传(Multifactorial Inheritance);器官测量(Organ Size)
DOI
10.1038/s41467-020-17376-1
PMID
32782260
发布时间
2021-08-11
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