ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing <i>Enterobacteriaceae</i>.

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作者： David T,Davies ^[1] ; Simon,Leiris ^[1] ; Nicolas,Sprynski ^[1] ; Jérôme,Castandet ^[1] ; Clarisse,Lozano ^[1] ; Justine,Bousquet ^[1] ; Magdalena,Zalacain ^[1] ; Srinivas,Vasa ^[2] ; Praveen K,Dasari ^[2] ; Ramesh,Pattipati ^[2] ; Naresh,Vempala ^[2] ; Swetha,Gujjewar ^[2] ; SyamKumar,Godi ^[2] ; Raju,Jallala ^[2] ; Rajashekar Reddy,Sathyap ^[2] ; Narasimha A,Darshanoju ^[2] ; Vengala R,Ravu ^[2] ; Ramakrishna R,Juventhala ^[2] ; Narender,Pottabathini ^[2] ; Somesh,Sharma ^[2] ; Srinivasu,Pothukanuri ^[2] ; Kirsty,Holden ^[3] ; Peter,Warn ^[3] ; Francesca,Marcoccia ^[4] ; Manuela,Benvenuti ^[5] ; Cecilia,Pozzi ^[5] ; Stefano,Mangani ^[5] ; Jean-Denis,Docquier ^[4] ; Marc,Lemonnier ^[1] ; Martin,Everett ^[1]

作者单位： Antabio SAS, 436 rue Pierre et Marie Curied, 31670 Labège, France. ^[1] Srinivas Vasa - GVK Biosciences Pvt. Ltd, Survey No. 125 and 126, IDA, Mallapur, Hyderabad-500 076, Telangana, India. ^[2] Evotec (U.K.) Ltd., Block 23, Alderley Park, Macclesfield, Cheshire, SK10 4TG, U.K. ^[3] Dipartimento di Biotecnologie Mediche, University of Siena, Viale Bracci 16, Siena, 53100, Italy. ^[4] Dipartimento di Biotecnologie, Chimica e Farmacia, University of Siena, Via Aldo Moro 2, Siena, 53100, Italy. ^[5]

关键词 ANT2681 New Delhi metallo-β-lactamase (NDM)antibiotic resistance carbapenem-resistant Enterobacteriaceae meropenem metallo-β-lactamase inhibitor

主题词抗菌药(Anti-Bacterial Agents);肠杆菌科(Enterobacteriaceae);单酰胺菌素类(Monobactams)

DOI 10.1021/acsinfecdis.0c00207

PMID 32786279

发布时间 2021-06-23

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ACS infectious diseases

2020年6卷9期

2419-2430页

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ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing <i>Enterobacteriaceae</i>.

ACS infectious diseases

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ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing <i>Enterobacteriaceae</i>.

ACS infectious diseases

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ACS infectious diseases

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