Effects of genomic copy number variants penetrant for schizophrenia on cortical thickness and surface area in healthy individuals: analysis of the UK Biobank.

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作者： Xavier,Caseras ^[1] ; George,Kirov ^[1] ; Kimberley M,Kendall ^[1] ; Elliott,Rees ^[1] ; Sophie E,Legge ^[1] ; Matthew,Bracher-Smith ^[1] ; Valentina,Escott-Price ^[2] ; Kevin,Murphy ^[3]

作者单位： MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, UK. ^[1] MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University; and UK Dementia Research Institute, Cardiff University, UK. ^[2] Cardiff University Brain Research Imaging Centre (CUBRIC), School of Physics and Astronomy, Cardiff University, UK. ^[3]

关键词 Imaging copy number variation cortical anatomy genetics schizophrenia

主题词生物标本库(Biological Specimen Banks);DNA拷贝数变异(DNA Copy Number Variations);疾病遗传易感性(Genetic Predisposition to Disease);基因组学(Genomics);人类(Humans);磁共振成像(Magnetic Resonance Imaging);精神分裂症(Schizophrenia)

DOI 10.1192/bjp.2020.139

PMID 32792019

发布时间 2023-11-15

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