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3'READS + RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association.

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第一作者： Dinghai,Zheng

第一单位： Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.

作者： Dinghai,Zheng ^[1] ; Hana,Cho ^[2] ; Wei,Wang ^[1] ; Xavier,Rambout ^[2] ; Bin,Tian ^[3] ; Lynne E,Maquat ^[2]

作者单位： Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA. ^[1] Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA.;Center for RNA Biology, University of Rochester, Rochester, New York 14642, USA. ^[2] Department of Microbiology, Biochemistry, and Molecular Genetics, Rutgers New Jersey Medical School, Newark, New Jersey 07103, USA.;Program in Gene Expression and Regulation, and Center for Systems and Computational Biology, Wistar Institute, Philadelphia, Pennsylvania 19104, USA. ^[3]

关键词 3′-untranslated regions Alu elements Staufen alternative polyadenylation mRNA isoforms mRNA-polysome association