Simultaneous identification of clinically relevant <i>RB1</i> mutations and copy number alterations in aqueous humor of retinoblastoma eyes.

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第一作者： Liya,Xu

第一单位： The Vision Center, Children's Hospital Los Angeles , Los Angeles, California, USA.

作者： Liya,Xu ^[1] ; Lishuang,Shen ^[2] ; Ashley,Polski ^[3] ; Rishvanth K,Prabakar ^[1] ; Rachana,Shah ^[4] ; Rima,Jubran ^[5] ; Jonathan W,Kim ^[6] ; Jacklyn,Biegel ^[6] ; Peter,Kuhn ^[1] ; David,Cobrinik ^[4] ; James,Hicks ^[3] ; Xiaowu,Gai ^[2] ; Jesse L,Berry ^[7]

作者单位： The Vision Center, Children's Hospital Los Angeles , Los Angeles, California, USA. ^[1] Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California , Los Angeles, California, USA. ^[2] Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles , Los Angeles, California, USA. ^[3] USC Roski Eye Institute, Keck School of Medicine of USC , Los Angeles, California, USA. ^[4] Department of Molecular and Computational Biology, University of Southern California , Los Angeles, California, USA. ^[5] Center for Blood Disorders, Children's Hospital Los Angeles , Los Angeles, California, USA. ^[6] Norris Comprehensive Cancer Center, Keck School of Medicine of USC , Los Angeles, California, USA. ^[7] Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California , Los Angeles, California, USA. ^[8] Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California , Los Angeles, California, USA. ^[9] The Saban Research Institute, Children's Hospital Los Angeles , Los Angeles, California, USA. ^[10] Department of Biochemistry and Molecular Medicine, Keck School of Medicine of USC , Los Angeles, California, USA. ^[11]

关键词 RB1 gene Aqueous humor mutational analysis retinoblastoma somatic copy number alterations