Right Ventricle Has Normal Myofilament Function But Shows Perturbations in the Expression of Extracellular Matrix Genes in Patients With Tetralogy of Fallot Undergoing Pulmonary Valve Replacement.
第一作者:
Daniel,Brayson
第一单位:
School of Cardiovascular Medicine and Sciences King's College London BHF Centre for Research Excellence London United Kingdom.
作者:
医学主题词
青少年(Adolescent);成年人(Adult);儿童(Child);胶原(Collagen);减量调节(Down-Regulation);细胞外基质(Extracellular Matrix);细胞外基质蛋白质类(Extracellular Matrix Proteins);女(雌)性(Female);基因表达(Gene Expression);基因表达谱(Gene Expression Profiling);心脏瓣膜假体植入(Heart Valve Prosthesis Implantation);人类(Humans);男(雄)性(Male);中年人(Middle Aged);肌收缩(Muscle Contraction);肌细胞, 心脏(Myocytes, Cardiac);肌原纤维(Myofibrils);聚合酶链反应(Polymerase Chain Reaction);肺动脉瓣(Pulmonary Valve);肺动脉瓣闭锁不全(Pulmonary Valve Insufficiency);RNA, 信使(RNA, Messenger);法乐四联症(Tetralogy of Fallot);增量调节(Up-Regulation);心室功能, 右(Ventricular Function, Right);青年人(Young Adult)
DOI
10.1161/JAHA.119.015342
PMID
32805183
发布时间
2025-05-30
基金项目
DH_/Department of Health/United Kingdom
PG/11/9/28705/BHF_/British Heart Foundation/United Kingdom
CH/16/3/32406/BHF_/British Heart Foundation/United Kingdom
RG/16/14/32397/BHF_/British Heart Foundation/United Kingdom
MC_UP_1502/3/MRC_/Medical Research Council/United Kingdom
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