Intranasal administration of regulatory dendritic cells is useful for the induction of nasal mucosal tolerance in a mice model of allergic rhinitis.

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作者： Motohiko,Suzuki ^[1] ; Makoto,Yokota ^[1] ; Yoshihiro,Kanemitsu ^[2] ; Wei-Ping,Min ^[3] ; Shinya,Ozaki ^[1] ; Yoshihisa,Nakamura ^[1]

作者单位： Departments of Otorhinolaryngology, Nagoya City University, Nagoya, Japan. ^[1] Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City, University, Nagoya, Japan. ^[2] Departments of Departments of Surgery, Microbiology and Immunology, and Pathology, University of Western Ontario, London, Canada. ^[3]

关键词 Allergic rhinitis Cervical lymph nodes DCs, dendritic cells Dendritic cells Intranasal administration OVA, ovalbumin PBS, phosphate-buffered saline Regulatory T cells i.n, intranasal i.p., intraperitoneal i.v., intravenous s.c., subcutaneous siRNA, small interfering RNA

DOI 10.1016/j.waojou.2020.100447

PMID 32817781

发布时间 2022-04-16

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