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Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.

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第一作者： Minervo,Perez

第一单位： Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA.

作者： Minervo,Perez ^[1] ; Daniel W,Bak ^[2] ; Sarah E,Bergholtz ^[1] ; Daniel R,Crooks ^[3] ; Bhargav Srinivas,Arimilli ^[3] ; Youfeng,Yang ^[3] ; Eranthie,Weerapana ^[2] ; W Marston,Linehan ^[3] ; Jordan L,Meier ^[4]

作者单位： Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA. ^[1] Department of Chemistry, Boston College, Chestnut Hill, Massachusetts, USA. ^[2] Urologic Oncology Branch, Center for Cancer Research, NCI, National Institutes of Health, Bethesda, Maryland, USA. ^[3] Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA. Electronic address: jordan.meier@nih.gov. ^[4]

关键词 TCA cycle chemical biology inborn error of metabolism metabolism mitochondria posttranslational modification (PTM)proteomics redox signaling tricarboxylic acid cycle (TCA cycle) (Krebs cycle)