4-Phenylbutyrate ameliorates apoptotic neural cell death in Down syndrome by reducing protein aggregates.

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作者： Katsuya,Hirata ^[1] ; Toshihiko,Nambara ^[2] ; Keiji,Kawatani ^[1] ; Nobutoshi,Nawa ^[1] ; Hidetaka,Yoshimatsu ^[1] ; Haruna,Kusakabe ^[1] ; Kimihiko,Banno ^[1] ; Ken,Nishimura ^[1] ; Manami,Ohtaka ^[3] ; Mahito,Nakanishi ^[4] ; Hidetoshi,Taniguchi ^[5] ; Hitomi,Arahori ^[6] ; Kazuko,Wada ^[5] ; Keiichi,Ozono ^[6] ; Yasuji,Kitabatake ^[1]

作者单位： Department of Pediatrics, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan. ^[1] Department of Neonatal Medicine, Osaka Women's and Children's Hospital, Izumi, Osaka, 594-1101, Japan. ^[2] Department of Physiology II, Nara Medical University, Kashihara, Nara, 634-8521, Japan. ^[3] Laboratory of Gene Regulation, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan. ^[4] Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, 305-8562, Japan. ^[5] TOKIWA-Bio, Inc, Tsukuba Center Inc. (TCI), Tsukuba, Ibaraki, 305-0047, Japan. ^[6] Department of Pediatrics, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan. ykitaba@ped.med.osaka-u.ac.jp. ^[7]