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Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo.

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第一作者： Amanda R,Wasylishen

第一单位： Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

作者： Amanda R,Wasylishen ^[1] ; Chang,Sun ^[2] ; Sydney M,Moyer ^[2] ; Yuan,Qi ^[3] ; Gilda P,Chau ^[1] ; Neeraj K,Aryal ^[2] ; Florencia,McAllister ^[4] ; Michael P,Kim ^[5] ; Michelle C,Barton ^[6] ; Jeannelyn S,Estrella ^[7] ; Xiaoping,Su ^[3] ; Guillermina,Lozano ^[2]

作者单位： Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[1] Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.;Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA. ^[2] Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[3] Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[4] Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[5] Genetics and Epigenetics Program, The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, Houston, TX 77030, USA.;Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[6] Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. ^[7]

医学主题词动物(Animals);辅阻遏蛋白质类(Co-Repressor Proteins);内源性逆转录病毒(Endogenous Retroviruses);小鼠(Mice);分子伴侣(Molecular Chaperones);神经内分泌瘤(Neuroendocrine Tumors);核蛋白质类(Nuclear Proteins);胰腺肿瘤(Pancreatic Neoplasms)

DOI 10.1126/sciadv.aba8415

PMID 32821827

发布时间 2024-04-28

基金项目

P30 CA016672/CA/NCI NIH HHS/United States R21 CA208463/CA/NCI NIH HHS/United States

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